BindingDB PrimarySearch

BDBM50079460 4-{5-[2-(3-Methoxy-phenyl)-ethyl]-3-phenyl-isoxazol-4-yl}-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester::CHEMBL539426

SMILES: CCOC(=O)C1C(c2c(CCc3cccc(OC)c3)onc2-c2ccccc2)C(C(=O)OCC)=C(C)N=C1C

InChI Key: InChIKey=KEUVWEPOTITQOY-UHFFFAOYSA-N

Data: 2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079460
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Calcium channel (RAT)	BDBM50079460 (4-{5-[2-(3-Methoxy-phenyl)-ethyl]-3-phenyl-isoxazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding from calcium channels of rat cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Calcium channel (Type L) (Homo sapiens (Human))	BDBM50079460 (4-{5-[2-(3-Methoxy-phenyl)-ethyl]-3-phenyl-isoxazo...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [3H](+)-PN200-110 binding to calcium channels in guinea pig cardiac membranes.				J Med Chem 42: 3087-93 (1999) Article DOI: 10.1021/jm980439q BindingDB Entry DOI: 10.7270/Q20C4TZD
State University of New York Curated by ChEMBL					More data for this Ligand-Target Pair