BDBM50079541 CHEMBL3417465

SMILES: CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3ccc(cc3)C(F)(F)F)ccc2=O)c1

InChI Key: InChIKey=PEQBNXUUGMARQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50079541 (CHEMBL3417465) Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(Nc3ccc(cc3)C(F)(F)F)ccc2=O)c1 Show InChI InChI=1S/C25H28F3N5O3/c1-32(2)14-3-4-15-36-24(35)30-21-7-5-6-18(16-21)17-33-23(34)13-12-22(31-33)29-20-10-8-19(9-11-20)25(26,27)28/h5-13,16H,3-4,14-15,17H2,1-2H3,(H,29,31)(H,30,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method				Eur J Med Chem 95: 302-12 (2015) Article DOI: 10.1016/j.ejmech.2015.03.041 BindingDB Entry DOI: 10.7270/Q2GQ70G4
					More data for this Ligand-Target Pair