BDBM50079555 CHEMBL3417479

SMILES: Fc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(NC(=O)OCCCCn5cccn5)c4)n3)c2c1

InChI Key: InChIKey=UEWOYJDYKUNDOP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50079555 (CHEMBL3417479) Show SMILES Fc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(NC(=O)OCCCCn5cccn5)c4)n3)c2c1 Show InChI InChI=1S/C27H25FN6O3/c28-22-8-7-21-11-15-33(24(21)18-22)25-9-10-26(35)34(31-25)19-20-5-3-6-23(17-20)30-27(36)37-16-2-1-13-32-14-4-12-29-32/h3-12,14-15,17-18H,1-2,13,16,19H2,(H,30,36)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method				Eur J Med Chem 95: 302-12 (2015) Article DOI: 10.1016/j.ejmech.2015.03.041 BindingDB Entry DOI: 10.7270/Q2GQ70G4
					More data for this Ligand-Target Pair