BDBM50079570 CHEMBL3417494

SMILES: COc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(NC(=O)OCCCCN(C)C)c4)n3)c2c1

InChI Key: InChIKey=KUVASXUIJUJUCO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50079570 (CHEMBL3417494) Show SMILES COc1ccc2ccn(-c3ccc(=O)n(Cc4cccc(NC(=O)OCCCCN(C)C)c4)n3)c2c1 Show InChI InChI=1S/C27H31N5O4/c1-30(2)14-4-5-16-36-27(34)28-22-8-6-7-20(17-22)19-32-26(33)12-11-25(29-32)31-15-13-21-9-10-23(35-3)18-24(21)31/h6-13,15,17-18H,4-5,14,16,19H2,1-3H3,(H,28,34)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	583	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method				Eur J Med Chem 95: 302-12 (2015) Article DOI: 10.1016/j.ejmech.2015.03.041 BindingDB Entry DOI: 10.7270/Q2GQ70G4
					More data for this Ligand-Target Pair