BDBM50079574 CHEMBL3417498

SMILES: CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3c(F)cc(F)cc23)c1

InChI Key: InChIKey=WCCNKOBFSVVEJN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079574   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50079574 (CHEMBL3417498) Show SMILES CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(ccc2=O)-n2ccc3c(F)cc(F)cc23)c1 Show InChI InChI=1S/C26H27F2N5O3/c1-31(2)11-3-4-13-36-26(35)29-20-7-5-6-18(14-20)17-33-25(34)9-8-24(30-33)32-12-10-21-22(28)15-19(27)16-23(21)32/h5-10,12,14-16H,3-4,11,13,17H2,1-2H3,(H,29,35)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 substrate incubated for 60 mins by ELISA method				Eur J Med Chem 95: 302-12 (2015) Article DOI: 10.1016/j.ejmech.2015.03.041 BindingDB Entry DOI: 10.7270/Q2GQ70G4
					More data for this Ligand-Target Pair