null

SMILES: CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O

InChI Key: InChIKey=DWVKVUXOQWIDLK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50079626   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079626 (CHEMBL3414769) Show SMILES CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O |c:1| Show InChI InChI=1S/C13H12N2O3/c1-7-8(2)13(18)15(12(7)17)10-5-3-4-9(6-10)11(14)16/h3-6H,1-2H3,(H2,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50079626 (CHEMBL3414769) Show SMILES CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O |c:1| Show InChI InChI=1S/C13H12N2O3/c1-7-8(2)13(18)15(12(7)17)10-5-3-4-9(6-10)11(14)16/h3-6H,1-2H3,(H2,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged full length human recombinant ARTD1 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosylt...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50079626 (CHEMBL3414769) Show SMILES CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O |c:1| Show InChI InChI=1S/C13H12N2O3/c1-7-8(2)13(18)15(12(7)17)10-5-3-4-9(6-10)11(14)16/h3-6H,1-2H3,(H2,14,16)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged full length human recombinant ARTD1 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosylt...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP15 (Homo sapiens (Human))	BDBM50079626 (CHEMBL3414769) Show SMILES CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O |c:1| Show InChI InChI=1S/C13H12N2O3/c1-7-8(2)13(18)15(12(7)17)10-5-3-4-9(6-10)11(14)16/h3-6H,1-2H3,(H2,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50079626 (CHEMBL3414769) Show SMILES CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O |c:1| Show InChI InChI=1S/C13H12N2O3/c1-7-8(2)13(18)15(12(7)17)10-5-3-4-9(6-10)11(14)16/h3-6H,1-2H3,(H2,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged full length human recombinant ARTD10 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosyl...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP14 (Homo sapiens (Human))	BDBM50079626 (CHEMBL3414769) Show SMILES CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O |c:1| Show InChI InChI=1S/C13H12N2O3/c1-7-8(2)13(18)15(12(7)17)10-5-3-4-9(6-10)11(14)16/h3-6H,1-2H3,(H2,14,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged human recombinant ARTD8 catalytic domain (1611 to 1801 amino acids) expressed in Escherichia coli BL21(DE3) assess...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50079626 (CHEMBL3414769) Show SMILES CC1=C(C)C(=O)N(C1=O)c1cccc(c1)C(N)=O |c:1| Show InChI InChI=1S/C13H12N2O3/c1-7-8(2)13(18)15(12(7)17)10-5-3-4-9(6-10)11(14)16/h3-6H,1-2H3,(H2,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Karolinska Institutet Curated by ChEMBL					Assay Description Inhibition of hexahistidine-tagged full length human recombinant ARTD10 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosyl...				Eur J Med Chem 95: 546-51 (2015) Article DOI: 10.1016/j.ejmech.2015.03.067 BindingDB Entry DOI: 10.7270/Q23J3FPJ
					More data for this Ligand-Target Pair