BDBM50079667 (S)-2-[3-({(4-Cyano-benzyl)-[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-methyl)-benzoylamino]-4-methylsulfanyl-butyric acid::CHEMBL61785

SMILES: CSCC[C@H](NC(=O)c1cccc(CN(Cc2cncn2Cc2ccc(cc2)C#N)Cc2ccc(cc2)C#N)c1)C(O)=O

InChI Key: InChIKey=UYKAYMDFMOZSIG-HKBQPEDESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50079667 ((S)-2-[3-({(4-Cyano-benzyl)-[3-(4-cyano-benzyl)-3H...) Show SMILES CSCC[C@H](NC(=O)c1cccc(CN(Cc2cncn2Cc2ccc(cc2)C#N)Cc2ccc(cc2)C#N)c1)C(O)=O Show InChI InChI=1S/C33H32N6O3S/c1-43-14-13-31(33(41)42)37-32(40)29-4-2-3-28(15-29)20-38(19-26-9-5-24(16-34)6-10-26)22-30-18-36-23-39(30)21-27-11-7-25(17-35)8-12-27/h2-12,15,18,23,31H,13-14,19-22H2,1H3,(H,37,40)(H,41,42)/t31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Reduction in the FTase-catalyzed (enzyme purified from bovine brain) incorporation of [3H]-FPP into recombinant Ha-Ras.				Bioorg Med Chem Lett 9: 1991-6 (1999) BindingDB Entry DOI: 10.7270/Q2ZG6RFB
					More data for this Ligand-Target Pair