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BDBM50079716 (5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hexaenoic acid (2,6-diisopropyl-phenyl)-amide::CHEMBL304267
SMILES: C\C=C\C\C=C\C\C=C\C\C=C\C\C=C\C\C=C\CCCC(=O)Nc1c(cccc1C(C)C)C(C)C
InChI Key: InChIKey=PURDMSRYPDDRFJ-BUHCESQUSA-N
Data: 9 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine adrenal gland | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from U937 microsome in human | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit intestine | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from canine liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50079716 ((5E,8E,11E,14E,17E,20E)-Docosa-5,8,11,14,17,20-hex...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Azwell Inc. Curated by ChEMBL | Assay Description Compound was tested for inhibitory activity against ACAT from rabbit liver | Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
