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BDBM50079815 1-[(4-Chloro-phenyl)-(2,3-dihydro-benzofuran-2-yl)-methyl]-1H-tetrazole::CHEMBL294357

SMILES: Clc1ccc(cc1)C(C1Cc2ccccc2O1)n1cnnn1

InChI Key: InChIKey=GXEUBSDSOQUBMV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079815   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aromatase (CYP19)


(Homo sapiens (Human))
BDBM50079815
PNG
(1-[(4-Chloro-phenyl)-(2,3-dihydro-benzofuran-2-yl)...)
Show SMILES Clc1ccc(cc1)C(C1Cc2ccccc2O1)n1cnnn1
Show InChI InChI=1S/C16H13ClN4O/c17-13-7-5-11(6-8-13)16(21-10-18-19-20-21)15-9-12-3-1-2-4-14(12)22-15/h1-8,10,15-16H,9H2
PDB
MMDB

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PC cid
PC sid
UniChem
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Cardiff University

Curated by ChEMBL


Assay Description
Inhibition of human placental aromatase, cytochrome P450 19A1


Bioorg Med Chem Lett 9: 2105-8 (1999)


BindingDB Entry DOI: 10.7270/Q2SQ8ZK7
More data for this
Ligand-Target Pair