BDBM50080037 Benzoic acid 4-((S)-2-{(S)-2-[(4-tert-butyl-benzyl)-methyl-amino]-4-methyl-pentanoylamino}-2-tert-butylcarbamoyl-ethyl)-phenyl ester::CHEMBL304309
SMILES: CC(C)C[C@H](N(C)Cc1ccc(cc1)C(C)(C)C)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C
InChI Key: InChIKey=HEPQIDBMXXAHTJ-LQJZCPKCSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human)) | BDBM50080037 (Benzoic acid 4-((S)-2-{(S)-2-[(4-tert-butyl-benzyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Inhibition of N-type calcium channels in IMR-32 human neuroblastoma cells | Bioorg Med Chem Lett 9: 2151-6 (1999) BindingDB Entry DOI: 10.7270/Q2H70F02 | |||||||||||
More data for this Ligand-Target Pair |