null

SMILES: CN1CCN(CC1)c1cccc2[nH]cnc12

InChI Key: InChIKey=VNORITPQZHTCHX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50080167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50080167 (4-(4-Methyl-piperazin-1-yl)-1H-benzoimidazole | 4-...) Show SMILES CN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C12H16N4/c1-15-5-7-16(8-6-15)11-4-2-3-10-12(11)14-9-13-10/h2-4,9H,5-8H2,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor was determined using [3H]-8-OH-DPAT as radioligand in rat cerebral cortex membranes				Bioorg Med Chem Lett 9: 2339-42 (1999) BindingDB Entry DOI: 10.7270/Q2M044MF
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50080167 (4-(4-Methyl-piperazin-1-yl)-1H-benzoimidazole | 4-...) Show SMILES CN1CCN(CC1)c1cccc2[nH]cnc12 Show InChI InChI=1S/C12H16N4/c1-15-5-7-16(8-6-15)11-4-2-3-10-12(11)14-9-13-10/h2-4,9H,5-8H2,1H3,(H,13,14)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells by liquid scintillation counting				J Med Chem 53: 1357-69 (2010) Article DOI: 10.1021/jm901672k BindingDB Entry DOI: 10.7270/Q2Z320KQ
					More data for this Ligand-Target Pair