BDBM50080274 Benzyl-phosphonic acid::CHEMBL299737::Phenyl-methanephosphonic acid anion::benzylphosphonic acid

SMILES: OP(O)(=O)Cc1ccccc1

InChI Key: InChIKey=OGBVRMYSNSKIEF-UHFFFAOYSA-N

Data: 5 KI  1 IC50  1 Kd

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50080274   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase placental type (Homo sapiens (Human))	BDBM50080274 (Benzyl-phosphonic acid | CHEMBL299737 | Phenyl-met...) Show SMILES OP(O)(=O)Cc1ccccc1 Show InChI InChI=1S/C7H9O3P/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Campinas Curated by ChEMBL					Assay Description Inhibition of human placental alkaline phosphatase using p-nitrophenyl phosphate substrate				Bioorg Med Chem 23: 4462-71 (2015) Article DOI: 10.1016/j.bmc.2015.06.017 BindingDB Entry DOI: 10.7270/Q2R78GZ7
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM50080274 (Benzyl-phosphonic acid | CHEMBL299737 | Phenyl-met...) Show SMILES OP(O)(=O)Cc1ccccc1 Show InChI InChI=1S/C7H9O3P/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Utah State University Curated by ChEMBL					Assay Description Inhibition of Human Placental alkaline Phosphatase (PLAP)				J Med Chem 46: 3703-8 (2003) Article DOI: 10.1021/jm030106f BindingDB Entry DOI: 10.7270/Q2MG7NXN
					More data for this Ligand-Target Pair
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (Bos taurus)	BDBM50080274 (Benzyl-phosphonic acid | CHEMBL299737 | Phenyl-met...) Show SMILES OP(O)(=O)Cc1ccccc1 Show InChI InChI=1S/C7H9O3P/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,10)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.40E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Campinas Curated by ChEMBL					Assay Description Inhibition of bovine intestinal 5'-nucleotide phosphodiesterase using 4-nitrophenyl phenylphosphonate substrate by spectrophotometry				Bioorg Med Chem 23: 4462-71 (2015) Article DOI: 10.1016/j.bmc.2015.06.017 BindingDB Entry DOI: 10.7270/Q2R78GZ7
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50080274 (Benzyl-phosphonic acid | CHEMBL299737 | Phenyl-met...) Show SMILES OP(O)(=O)Cc1ccccc1 Show InChI InChI=1S/C7H9O3P/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Campinas Curated by ChEMBL					Assay Description Inhibition of PTP1B (unknown origin) using nPP substrate				Bioorg Med Chem 23: 4462-71 (2015) Article DOI: 10.1016/j.bmc.2015.06.017 BindingDB Entry DOI: 10.7270/Q2R78GZ7
					More data for this Ligand-Target Pair
Mandelate racemase (MR) (Pseudomonas putida (g-Proteobacteria))	BDBM50080274 (Benzyl-phosphonic acid | CHEMBL299737 | Phenyl-met...) Show SMILES OP(O)(=O)Cc1ccccc1 Show InChI InChI=1S/C7H9O3P/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,10)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	3.60E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Dalhousie University Curated by ChEMBL					Assay Description Inhibition constant against Mandelate racemase from Pseudomonas putida at pH 7.5				Bioorg Med Chem Lett 13: 2041-4 (2003) BindingDB Entry DOI: 10.7270/Q2XP75HB
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50080274 (Benzyl-phosphonic acid | CHEMBL299737 | Phenyl-met...) Show SMILES OP(O)(=O)Cc1ccccc1 Show InChI InChI=1S/C7H9O3P/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,10)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	5.90E+6	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against Lck SH2 domain				Bioorg Med Chem Lett 9: 2403-6 (1999) BindingDB Entry DOI: 10.7270/Q2Z89BK7
					More data for this Ligand-Target Pair
Prostatic acid phosphatase (Homo sapiens (Human))	BDBM50080274 (Benzyl-phosphonic acid | CHEMBL299737 | Phenyl-met...) Show SMILES OP(O)(=O)Cc1ccccc1 Show InChI InChI=1S/C7H9O3P/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human prostatic acid phosphatase was determined as inhibition of the hydrolysis of tyrosine phosphate				Bioorg Med Chem Lett 6: 311-314 (1996) Article DOI: 10.1016/0960-894X(96)00018-2 BindingDB Entry DOI: 10.7270/Q21R6QGR
					More data for this Ligand-Target Pair