BDBM50080404 CHEMBL3422262

SMILES: CN(C)CCOc1cc(Cl)c(C)cc1NC(=O)NCc1ccc(Oc2ccnc(NC(C)=O)c2)c(C)c1

InChI Key: InChIKey=MEZJAJUCIVBWKG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080404   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50080404 (CHEMBL3422262) Show SMILES CN(C)CCOc1cc(Cl)c(C)cc1NC(=O)NCc1ccc(Oc2ccnc(NC(C)=O)c2)c(C)c1 Show InChI InChI=1S/C27H32ClN5O4/c1-17-13-23(25(15-22(17)28)36-11-10-33(4)5)32-27(35)30-16-20-6-7-24(18(2)12-20)37-21-8-9-29-26(14-21)31-19(3)34/h6-9,12-15H,10-11,16H2,1-5H3,(H,29,31,34)(H2,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human DDR2 expressed in HEK293 cells assessed as reduction in collagen-2-induced DDR2 phosphorylation				J Med Chem 58: 3287-301 (2015) Article DOI: 10.1021/jm5012319 BindingDB Entry DOI: 10.7270/Q2DV1MMV
					More data for this Ligand-Target Pair