BDBM50080698 2-Methylamino-N-{4-[3-methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2Z)-ylidenesulfamoyl]-phenyl}-acetamide::CHEMBL123606

SMILES: CNCC(=O)Nc1ccc(cc1)S(=O)(=O)\N=c1/sc(nn1C)S(N)(=O)=O

InChI Key: InChIKey=WQNDOASZRAMVMT-BOPFTXTBSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50080698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50080698 (2-Methylamino-N-{4-[3-methyl-5-sulfamoyl-3H-[1,3,4...) Show SMILES CNCC(=O)Nc1ccc(cc1)S(=O)(=O)\N=c1/sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C12H16N6O5S3/c1-14-7-10(19)15-8-3-5-9(6-4-8)26(22,23)17-11-18(2)16-12(24-11)25(13,20)21/h3-6,14H,7H2,1-2H3,(H,15,19)(H2,13,20,21)/b17-11-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant carbonic anhydrase II (CA2)				J Med Chem 42: 3690-700 (1999) Article DOI: 10.1021/jm9901879 BindingDB Entry DOI: 10.7270/Q26Q1XXC
					More data for this Ligand-Target Pair
Carbonic Anhydrase IV (Bos taurus (bovine))	BDBM50080698 (2-Methylamino-N-{4-[3-methyl-5-sulfamoyl-3H-[1,3,4...) Show SMILES CNCC(=O)Nc1ccc(cc1)S(=O)(=O)\N=c1/sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C12H16N6O5S3/c1-14-7-10(19)15-8-3-5-9(6-4-8)26(22,23)17-11-18(2)16-12(24-11)25(13,20)21/h3-6,14H,7H2,1-2H3,(H,15,19)(H2,13,20,21)/b17-11-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against bovine carbonic anhydrase IV (CA4), isolated from bovine lung microsomes				J Med Chem 42: 3690-700 (1999) Article DOI: 10.1021/jm9901879 BindingDB Entry DOI: 10.7270/Q26Q1XXC
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50080698 (2-Methylamino-N-{4-[3-methyl-5-sulfamoyl-3H-[1,3,4...) Show SMILES CNCC(=O)Nc1ccc(cc1)S(=O)(=O)\N=c1/sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C12H16N6O5S3/c1-14-7-10(19)15-8-3-5-9(6-4-8)26(22,23)17-11-18(2)16-12(24-11)25(13,20)21/h3-6,14H,7H2,1-2H3,(H,15,19)(H2,13,20,21)/b17-11-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant carbonic anhydrase I (CA1)				J Med Chem 42: 3690-700 (1999) Article DOI: 10.1021/jm9901879 BindingDB Entry DOI: 10.7270/Q26Q1XXC
					More data for this Ligand-Target Pair