BDBM50080791 7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-chromen-2-one::CHEMBL125763

SMILES: Clc1ccc(cc1)N1CCN(Cc2ccc3ccc(=O)oc3c2)CC1

InChI Key: InChIKey=LVOJJZXFKVDALQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50080791 (7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-chrom...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2ccc3ccc(=O)oc3c2)CC1 Show InChI InChI=1S/C20H19ClN2O2/c21-17-4-6-18(7-5-17)23-11-9-22(10-12-23)14-15-1-2-16-3-8-20(24)25-19(16)13-15/h1-8,13H,9-12,14H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2				J Med Chem 42: 3718-25 (1999) Article DOI: 10.1021/jm990266k BindingDB Entry DOI: 10.7270/Q2RN371G
					More data for this Ligand-Target Pair