BDBM50080795 7-(4-m-Tolyl-piperazin-1-ylmethyl)-chromen-2-one::CHEMBL431479

SMILES: Cc1cccc(c1)N1CCN(Cc2ccc3ccc(=O)oc3c2)CC1

InChI Key: InChIKey=GDEFYDCIVUNWDO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50080795 (7-(4-m-Tolyl-piperazin-1-ylmethyl)-chromen-2-one |...) Show SMILES Cc1cccc(c1)N1CCN(Cc2ccc3ccc(=O)oc3c2)CC1 Show InChI InChI=1S/C21H22N2O2/c1-16-3-2-4-19(13-16)23-11-9-22(10-12-23)15-17-5-6-18-7-8-21(24)25-20(18)14-17/h2-8,13-14H,9-12,15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2				J Med Chem 42: 3718-25 (1999) Article DOI: 10.1021/jm990266k BindingDB Entry DOI: 10.7270/Q2RN371G
					More data for this Ligand-Target Pair