BDBM50080809 7-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-chromen-2-one::CHEMBL332001

SMILES: O=c1ccc2ccc(CN3CCC(=CC3)c3ccccc3)cc2o1

InChI Key: InChIKey=LWXHXQVCGRSPNP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50080809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50080809 (7-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-chr...) Show SMILES O=c1ccc2ccc(CN3CCC(=CC3)c3ccccc3)cc2o1 |c:12| Show InChI InChI=1S/C21H19NO2/c23-21-9-8-19-7-6-16(14-20(19)24-21)15-22-12-10-18(11-13-22)17-4-2-1-3-5-17/h1-10,14H,11-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2				J Med Chem 42: 3718-25 (1999) Article DOI: 10.1021/jm990266k BindingDB Entry DOI: 10.7270/Q2RN371G
					More data for this Ligand-Target Pair