BDBM50080885 Benzamidrazone analogue::CHEMBL79304
SMILES: COc1ccc2cc(ccc2c1)S(=O)(=O)N[C@@H](Cc1ccc(cc1F)C(N)=NN)C(=O)N(C)C1CCCC1
InChI Key: InChIKey=BSIWRNJURNSESA-VWLOTQADSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50080885 (Benzamidrazone analogue | CHEMBL79304) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biotech Research Institute Curated by ChEMBL | Assay Description Inhibitory constant of the compound against human thrombin was determined in vitro. | Bioorg Med Chem Lett 9: 2483-6 (1999) BindingDB Entry DOI: 10.7270/Q2CC0ZW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Bos taurus (bovine)) | BDBM50080885 (Benzamidrazone analogue | CHEMBL79304) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biotech Research Institute Curated by ChEMBL | Assay Description Inhibitory constant of the compound against bovine trypsin was determined in vitro. | Bioorg Med Chem Lett 9: 2483-6 (1999) BindingDB Entry DOI: 10.7270/Q2CC0ZW2 | |||||||||||
More data for this Ligand-Target Pair |