BDBM50081005 7-Methoxy-naphthalene-2-sulfonic acid [1-(2-amino-quinolin-6-ylmethyl)-2-oxo-pyrrolidin-3-yl]-amide::CHEMBL86343

SMILES: COc1ccc2ccc(cc2c1)S(=O)(=O)NC1CCN(Cc2ccc3nc(N)ccc3c2)C1=O

InChI Key: InChIKey=QTMHKYIZBVUMKD-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50081005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Bos taurus)	BDBM50081005 (7-Methoxy-naphthalene-2-sulfonic acid [1-(2-amino-...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)NC1CCN(Cc2ccc3nc(N)ccc3c2)C1=O Show InChI InChI=1S/C25H24N4O4S/c1-33-20-6-3-17-4-7-21(14-19(17)13-20)34(31,32)28-23-10-11-29(25(23)30)15-16-2-8-22-18(12-16)5-9-24(26)27-22/h2-9,12-14,23,28H,10-11,15H2,1H3,(H2,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description In vitro evaluation of inhibitory activity against Coagulation factor X in prothrombinase complex				Bioorg Med Chem Lett 9: 2539-44 (1999) BindingDB Entry DOI: 10.7270/Q21R6R1B
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50081005 (7-Methoxy-naphthalene-2-sulfonic acid [1-(2-amino-...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)NC1CCN(Cc2ccc3nc(N)ccc3c2)C1=O Show InChI InChI=1S/C25H24N4O4S/c1-33-20-6-3-17-4-7-21(14-19(17)13-20)34(31,32)28-23-10-11-29(25(23)30)15-16-2-8-22-18(12-16)5-9-24(26)27-22/h2-9,12-14,23,28H,10-11,15H2,1H3,(H2,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description In vitro evaluation of inhibitory activity against trypsin				Bioorg Med Chem Lett 9: 2539-44 (1999) BindingDB Entry DOI: 10.7270/Q21R6R1B
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50081005 (7-Methoxy-naphthalene-2-sulfonic acid [1-(2-amino-...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)NC1CCN(Cc2ccc3nc(N)ccc3c2)C1=O Show InChI InChI=1S/C25H24N4O4S/c1-33-20-6-3-17-4-7-21(14-19(17)13-20)34(31,32)28-23-10-11-29(25(23)30)15-16-2-8-22-18(12-16)5-9-24(26)27-22/h2-9,12-14,23,28H,10-11,15H2,1H3,(H2,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description In vitro evaluation of inhibitory activity against Coagulation factor II in prothrombinase complex				Bioorg Med Chem Lett 9: 2539-44 (1999) BindingDB Entry DOI: 10.7270/Q21R6R1B
					More data for this Ligand-Target Pair