BDBM50081010 7-Methoxy-naphthalene-2-sulfonic acid [(S)-1-(1-chloro-isoquinolin-7-ylmethyl)-2-oxo-pyrrolidin-3-yl]-amide::CHEMBL315372

SMILES: COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2ccc3ccnc(Cl)c3c2)C1=O

InChI Key: InChIKey=OVNAHQFKHOJAIQ-QHCPKHFHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081010   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Bos taurus)	BDBM50081010 (7-Methoxy-naphthalene-2-sulfonic acid [(S)-1-(1-ch...) Show SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2ccc3ccnc(Cl)c3c2)C1=O Show InChI InChI=1S/C25H22ClN3O4S/c1-33-20-6-4-17-5-7-21(14-19(17)13-20)34(31,32)28-23-9-11-29(25(23)30)15-16-2-3-18-8-10-27-24(26)22(18)12-16/h2-8,10,12-14,23,28H,9,11,15H2,1H3/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rh£ne-Poulenc Rorer Curated by ChEMBL					Assay Description In vitro evaluation of inhibitory activity against Coagulation factor X in prothrombinase complex				Bioorg Med Chem Lett 9: 2539-44 (1999) BindingDB Entry DOI: 10.7270/Q21R6R1B
					More data for this Ligand-Target Pair