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BDBM50081157 (S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-ylcarbamoyl)-methyl]-2-oxo-3-phenylmethanesulfonylamino-piperidine-3-carboxylic acid ethyl ester::CHEMBL329865

SMILES: CCOC(=O)[C@@]1(CCCN(CC(=O)N[C@H]2CCCN(C2O)C(N)=N)C1=O)NS(=O)(=O)Cc1ccccc1

InChI Key: InChIKey=YLPFNSPUPARBLY-BSZRCVNOSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081157   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50081157
PNG
((S)-1-[((S)-1-Carbamimidoyl-2-hydroxy-piperidin-3-...)
Show SMILES CCOC(=O)[C@@]1(CCCN(CC(=O)N[C@H]2CCCN(C2O)C(N)=N)C1=O)NS(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C23H34N6O7S/c1-2-36-21(33)23(27-37(34,35)15-16-8-4-3-5-9-16)11-7-12-28(20(23)32)14-18(30)26-17-10-6-13-29(19(17)31)22(24)25/h3-5,8-9,17,19,27,31H,2,6-7,10-15H2,1H3,(H3,24,25)(H,26,30)/t17-,19?,23-/m0/s1
PDB

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PC sid
UniChem

Similars
PubMed
 1n/an/an/an/an/an/an/an/a



Corvas International, Inc.

Curated by ChEMBL


Assay Description
Evaluation of inhibition of transition state thrombin

Bioorg Med Chem Lett 9: 2625-8 (1999)


BindingDB Entry DOI: 10.7270/Q2JW8D3W
More data for this
Ligand-Target Pair