BDBM50081224 2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-phenyl)-ureido]-ethyl}-phenoxy)-2-methyl-propionic acid::CHEMBL125230

SMILES: CC(C)(Oc1ccc(CCN(CCCCCC2CCCCC2)C(=O)Nc2ccc(F)cc2)cc1)C(O)=O

InChI Key: InChIKey=VVLHLZMVXTZBDF-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50081224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50081224 (2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-pheny...) Show SMILES CC(C)(Oc1ccc(CCN(CCCCCC2CCCCC2)C(=O)Nc2ccc(F)cc2)cc1)C(O)=O Show InChI InChI=1S/C30H41FN2O4/c1-30(2,28(34)35)37-27-18-12-24(13-19-27)20-22-33(29(36)32-26-16-14-25(31)15-17-26)21-8-4-7-11-23-9-5-3-6-10-23/h12-19,23H,3-11,20-22H2,1-2H3,(H,32,36)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor gamma-Gal4 chimeric receptor in transfected CV...				J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mus musculus)	BDBM50081224 (2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-pheny...) Show SMILES CC(C)(Oc1ccc(CCN(CCCCCC2CCCCC2)C(=O)Nc2ccc(F)cc2)cc1)C(O)=O Show InChI InChI=1S/C30H41FN2O4/c1-30(2,28(34)35)37-27-18-12-24(13-19-27)20-22-33(29(36)32-26-16-14-25(31)15-17-26)21-8-4-7-11-23-9-5-3-6-10-23/h12-19,23H,3-11,20-22H2,1-2H3,(H,32,36)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor transfected CV-1 ...				J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50081224 (2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-pheny...) Show SMILES CC(C)(Oc1ccc(CCN(CCCCCC2CCCCC2)C(=O)Nc2ccc(F)cc2)cc1)C(O)=O Show InChI InChI=1S/C30H41FN2O4/c1-30(2,28(34)35)37-27-18-12-24(13-19-27)20-22-33(29(36)32-26-16-14-25(31)15-17-26)21-8-4-7-11-23-9-5-3-6-10-23/h12-19,23H,3-11,20-22H2,1-2H3,(H,32,36)(H,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Compound was tested for agonist activity on human Peroxisome proliferator activated receptor gamma-Gal4 chimeric receptor in transfected CV-1 cells				J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50081224 (2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-pheny...) Show SMILES CC(C)(Oc1ccc(CCN(CCCCCC2CCCCC2)C(=O)Nc2ccc(F)cc2)cc1)C(O)=O Show InChI InChI=1S/C30H41FN2O4/c1-30(2,28(34)35)37-27-18-12-24(13-19-27)20-22-33(29(36)32-26-16-14-25(31)15-17-26)21-8-4-7-11-23-9-5-3-6-10-23/h12-19,23H,3-11,20-22H2,1-2H3,(H,32,36)(H,34,35)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Compound was tested for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected CV-1 cells				J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Mus musculus)	BDBM50081224 (2-(4-{2-[1-(5-Cyclohexyl-pentyl)-3-(4-fluoro-pheny...) Show SMILES CC(C)(Oc1ccc(CCN(CCCCCC2CCCCC2)C(=O)Nc2ccc(F)cc2)cc1)C(O)=O Show InChI InChI=1S/C30H41FN2O4/c1-30(2,28(34)35)37-27-18-12-24(13-19-27)20-22-33(29(36)32-26-16-14-25(31)15-17-26)21-8-4-7-11-23-9-5-3-6-10-23/h12-19,23H,3-11,20-22H2,1-2H3,(H,32,36)(H,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a
Glaxo Wellcome Research & Development Curated by ChEMBL					Assay Description Compound was tested for its agonist activity against murine Peroxisome proliferator activated receptor delta-GAL4 chimeric receptor in transfected CV...				J Med Chem 42: 3785-8 (1999) BindingDB Entry DOI: 10.7270/Q29C6WM9
					More data for this Ligand-Target Pair