Found 4 hits for monomerid = 50081442 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP1 subtype (EP1)
(Homo sapiens (Human)) | BDBM50081442
(CHEMBL90226 | sulfonylurea analogue)Show SMILES O=C(NCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C36H31N3O4S/c40-35-32-15-6-4-12-28(32)22-23-30-13-5-8-16-33(30)39(35)25-27-18-20-29(21-19-27)31-14-7-9-17-34(31)44(42,43)38-36(41)37-24-26-10-2-1-3-11-26/h1-21H,22-25H2,(H2,37,38,41) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP1 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor
(Homo sapiens (Human)) | BDBM50081442
(CHEMBL90226 | sulfonylurea analogue)Show SMILES O=C(NCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C36H31N3O4S/c40-35-32-15-6-4-12-28(32)22-23-30-13-5-8-16-33(30)39(35)25-27-18-20-29(21-19-27)31-14-7-9-17-34(31)44(42,43)38-36(41)37-24-26-10-2-1-3-11-26/h1-21H,22-25H2,(H2,37,38,41) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP3 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50081442
(CHEMBL90226 | sulfonylurea analogue)Show SMILES O=C(NCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C36H31N3O4S/c40-35-32-15-6-4-12-28(32)22-23-30-13-5-8-16-33(30)39(35)25-27-18-20-29(21-19-27)31-14-7-9-17-34(31)44(42,43)38-36(41)37-24-26-10-2-1-3-11-26/h1-21H,22-25H2,(H2,37,38,41) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP4 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50081442
(CHEMBL90226 | sulfonylurea analogue)Show SMILES O=C(NCc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C36H31N3O4S/c40-35-32-15-6-4-12-28(32)22-23-30-13-5-8-16-33(30)39(35)25-27-18-20-29(21-19-27)31-14-7-9-17-34(31)44(42,43)38-36(41)37-24-26-10-2-1-3-11-26/h1-21H,22-25H2,(H2,37,38,41) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP2 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |