Found 4 hits for monomerid = 50081446 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin E2 receptor EP1 subtype (EP1)
(Homo sapiens (Human)) | BDBM50081446
(CHEMBL91270 | sulfonylurea analogue)Show SMILES CCCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C33H33N3O4S/c1-2-3-22-34-33(38)35-41(39,40)31-15-9-7-12-28(31)26-18-16-24(17-19-26)23-36-30-14-8-5-11-27(30)21-20-25-10-4-6-13-29(25)32(36)37/h4-19H,2-3,20-23H2,1H3,(H2,34,35,38) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP1 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor
(Homo sapiens (Human)) | BDBM50081446
(CHEMBL91270 | sulfonylurea analogue)Show SMILES CCCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C33H33N3O4S/c1-2-3-22-34-33(38)35-41(39,40)31-15-9-7-12-28(31)26-18-16-24(17-19-26)23-36-30-14-8-5-11-27(30)21-20-25-10-4-6-13-29(25)32(36)37/h4-19H,2-3,20-23H2,1H3,(H2,34,35,38) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP3 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human)) | BDBM50081446
(CHEMBL91270 | sulfonylurea analogue)Show SMILES CCCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C33H33N3O4S/c1-2-3-22-34-33(38)35-41(39,40)31-15-9-7-12-28(31)26-18-16-24(17-19-26)23-36-30-14-8-5-11-27(30)21-20-25-10-4-6-13-29(25)32(36)37/h4-19H,2-3,20-23H2,1H3,(H2,34,35,38) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP4 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human)) | BDBM50081446
(CHEMBL91270 | sulfonylurea analogue)Show SMILES CCCCNC(=O)NS(=O)(=O)c1ccccc1-c1ccc(CN2c3ccccc3CCc3ccccc3C2=O)cc1 Show InChI InChI=1S/C33H33N3O4S/c1-2-3-22-34-33(38)35-41(39,40)31-15-9-7-12-28(31)26-18-16-24(17-19-26)23-36-30-14-8-5-11-27(30)21-20-25-10-4-6-13-29(25)32(36)37/h4-19H,2-3,20-23H2,1H3,(H2,34,35,38) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description Affinity at human EP2 receptor. |
Bioorg Med Chem Lett 9: 2699-704 (1999)
BindingDB Entry DOI: 10.7270/Q2HX1BV9 |
More data for this Ligand-Target Pair | |