BDBM50081457 1-(5-Bromo-pyridin-2-yl)-3-(2-cyclohex-1-enyl-ethyl)-thiourea::CHEMBL93822::HI-346

SMILES: Brc1ccc(NC(=S)NCCC2=CCCCC2)nc1

InChI Key: InChIKey=DMUWBIHBABUYBI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081457   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50081457 (1-(5-Bromo-pyridin-2-yl)-3-(2-cyclohex-1-enyl-ethy...) Show SMILES Brc1ccc(NC(=S)NCCC2=CCCCC2)nc1 |t:11| Show InChI InChI=1S/C14H18BrN3S/c15-12-6-7-13(17-10-12)18-14(19)16-9-8-11-4-2-1-3-5-11/h4,6-7,10H,1-3,5,8-9H2,(H2,16,17,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant HIV-1 reverse transcriptase (rRT)				Bioorg Med Chem Lett 9: 2721-6 (1999) BindingDB Entry DOI: 10.7270/Q2D50M49
					More data for this Ligand-Target Pair