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BDBM50081490 5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrimidine::CHEMBL329682

SMILES: CN1CCC[C@H]1COc1cncnc1

InChI Key: InChIKey=YNDCHCKPYHFVAW-VIFPVBQESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50081490   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Rattus norvegicus (Rat))
BDBM50081490
PNG
(5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyrimidine...)
Show SMILES CN1CCC[C@H]1COc1cncnc1
Show InChI InChI=1S/C10H15N3O/c1-13-4-2-3-9(13)7-14-10-5-11-8-12-6-10/h5-6,8-9H,2-4,7H2,1H3/t9-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
2.40n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...


Bioorg Med Chem Lett 9: 2747-52 (1999)


BindingDB Entry DOI: 10.7270/Q20Z72HG
More data for this
Ligand-Target Pair