BDBM50081496 5-((S)-1-Azetidin-2-ylmethoxy)-pyrimidine::CHEMBL328705

SMILES: C(Oc1cncnc1)[C@@H]1CCN1

InChI Key: InChIKey=XOYWIKDUNYLVAF-ZETCQYMHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50081496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50081496 (5-((S)-1-Azetidin-2-ylmethoxy)-pyrimidine | CHEMBL...) Show SMILES C(Oc1cncnc1)[C@@H]1CCN1 Show InChI InChI=1S/C8H11N3O/c1-2-11-7(1)5-12-8-3-9-6-10-4-8/h3-4,6-7,11H,1-2,5H2/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [3H]- (-) cytisine binding from whole rat bra...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair
Nicotinic acetylcholine receptor alpha9/alpha10 (Rattus norvegicus)	BDBM50081496 (5-((S)-1-Azetidin-2-ylmethoxy)-pyrimidine | CHEMBL...) Show SMILES C(Oc1cncnc1)[C@@H]1CCN1 Show InChI InChI=1S/C8H11N3O/c1-2-11-7(1)5-12-8-3-9-6-10-4-8/h3-4,6-7,11H,1-2,5H2/t7-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Nicotinic acetylcholine receptor binding activity was determined by ability of the compound to displace [125I]-alpha-BgT binding to rat brain membran...				Bioorg Med Chem Lett 9: 2747-52 (1999) BindingDB Entry DOI: 10.7270/Q20Z72HG
					More data for this Ligand-Target Pair