BDBM50081513 3-[(S)-3-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-2-oxo-pyrrolidin-1-ylmethyl]-benzamidine::CHEMBL418958
SMILES: Cc1c(sc2ccc(Cl)cc12)S(=O)(=O)N[C@H]1CCN(Cc2cccc(c2)C(N)=N)C1=O
InChI Key: InChIKey=LQWIPPFSKXCADI-KRWDZBQOSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50081513 (3-[(S)-3-(5-Chloro-3-methyl-benzo[b]thiophene-2-su...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rhône-Poulenc Rorer Curated by ChEMBL | Assay Description Binding affinity against serine protease Coagulation factor X | Bioorg Med Chem Lett 9: 2753-8 (1999) BindingDB Entry DOI: 10.7270/Q2W66K02 | |||||||||||
More data for this Ligand-Target Pair |