BDBM50082184 3-[3-Oxo-3-piperidin-1-yl-2-(2,4,6-triisopropyl-benzenesulfonylamino)-propyl]-benzamidine::CHEMBL324188

SMILES: CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1

InChI Key: InChIKey=KQJFAHLTPFDWFI-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50082184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin II (Bos taurus)	BDBM50082184 (3-[3-Oxo-3-piperidin-1-yl-2-(2,4,6-triisopropyl-be...) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 Show InChI InChI=1S/C30H44N4O3S/c1-19(2)24-17-25(20(3)4)28(26(18-24)21(5)6)38(36,37)33-27(30(35)34-13-8-7-9-14-34)16-22-11-10-12-23(15-22)29(31)32/h10-12,15,17-21,27,33H,7-9,13-14,16H2,1-6H3,(H3,31,32)	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Jena Curated by ChEMBL					Assay Description Tested for inhibition of trypsin				Bioorg Med Chem Lett 9: 3147-52 (1999) BindingDB Entry DOI: 10.7270/Q2RB73S3
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50082184 (3-[3-Oxo-3-piperidin-1-yl-2-(2,4,6-triisopropyl-be...) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 Show InChI InChI=1S/C30H44N4O3S/c1-19(2)24-17-25(20(3)4)28(26(18-24)21(5)6)38(36,37)33-27(30(35)34-13-8-7-9-14-34)16-22-11-10-12-23(15-22)29(31)32/h10-12,15,17-21,27,33H,7-9,13-14,16H2,1-6H3,(H3,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Jena Curated by ChEMBL					Assay Description Tested for inhibition of plasmin				Bioorg Med Chem Lett 9: 3147-52 (1999) BindingDB Entry DOI: 10.7270/Q2RB73S3
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50082184 (3-[3-Oxo-3-piperidin-1-yl-2-(2,4,6-triisopropyl-be...) Show SMILES CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)NC(Cc1cccc(c1)C(N)=N)C(=O)N1CCCCC1 Show InChI InChI=1S/C30H44N4O3S/c1-19(2)24-17-25(20(3)4)28(26(18-24)21(5)6)38(36,37)33-27(30(35)34-13-8-7-9-14-34)16-22-11-10-12-23(15-22)29(31)32/h10-12,15,17-21,27,33H,7-9,13-14,16H2,1-6H3,(H3,31,32)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universität Jena Curated by ChEMBL					Assay Description Tested for inhibition of plasminogen activator urokinase (microPa)				Bioorg Med Chem Lett 9: 3147-52 (1999) BindingDB Entry DOI: 10.7270/Q2RB73S3
					More data for this Ligand-Target Pair