BDBM50082230 (2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)-2-(6,7-difluoro-naphthalen-2-ylmethyl)-3,N*4*-dihydroxy-succinamide::CHEMBL110617

SMILES: CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccc2cc(F)c(F)cc2c1)[C@H](O)C(=O)NO)C(N)=O

InChI Key: InChIKey=GPIRSWQBXHWGSJ-XOKHGSTOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Immunoglobulin epsilon Fc receptor (Homo sapiens (Human))	BDBM50082230 ((2R,3S)-N*1*-((S)-1-Carbamoyl-2,2-dimethyl-propyl)...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](Cc1ccc2cc(F)c(F)cc2c1)[C@H](O)C(=O)NO)C(N)=O Show InChI InChI=1S/C21H25F2N3O5/c1-21(2,3)17(18(24)28)25-19(29)13(16(27)20(30)26-31)7-10-4-5-11-8-14(22)15(23)9-12(11)6-10/h4-6,8-9,13,16-17,27,31H,7H2,1-3H3,(H2,24,28)(H,25,29)(H,26,30)/t13-,16+,17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against IgE receptor				Bioorg Med Chem Lett 9: 3165-70 (1999) BindingDB Entry DOI: 10.7270/Q2MK6C37
					More data for this Ligand-Target Pair