BDBM50082319 (R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-yl]-propan-2-ol; hydrochloride::CHEMBL554228
SMILES: O[C@@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1
InChI Key: InChIKey=FXLWBYZTEVJBSX-HSZRJFAPSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type I I alpha subunit (Rattus norvegicus) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type I I alpha subunit (Rattus norvegicus) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair |