BDBM50082568 2-({3-[4-(2-Azido-benzenesulfonylaminocarbonyl)-benzyl]-2-butyl-3H-imidazol-4-ylmethyl}-amino)-benzoic acid::CHEMBL143118
SMILES: CCCCc1ncc(CNc2ccccc2C(O)=O)n1Cc1ccc(cc1)C(=O)NS(=O)(=O)c1ccccc1N=[N+]=[N-]
InChI Key: InChIKey=SKTCIXGMPLITJZ-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Type-1A angiotensin II receptor (RAT) | BDBM50082568 (2-({3-[4-(2-Azido-benzenesulfonylaminocarbonyl)-be...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoires Fournier S.A. Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of [125I]-Sar-AII binding to Angiotensin II receptor, type 1 from purified rat liver membranes. | J Med Chem 42: 4572-83 (1999) BindingDB Entry DOI: 10.7270/Q2XW4J1J | |||||||||||
More data for this Ligand-Target Pair |