BDBM50082730 4-(4-Chloro-phenyl)-1-(4,4-diphenyl-butyl)-4-hydroxy-piperidinium; iodide::CHEMBL142004

SMILES: OC1(CC[NH+](CCCC(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=LLQCATMGHGFZSS-UHFFFAOYSA-O

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50082730   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50082730 (4-(4-Chloro-phenyl)-1-(4,4-diphenyl-butyl)-4-hydro...) Show SMILES OC1(CC[NH+](CCCC(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 |(10.24,-13.6,;9.18,-14.69,;8.45,-13.32,;6.91,-13.28,;5.59,-14.67,;4.76,-13.81,;4.76,-12.27,;3.43,-11.48,;3.43,-9.94,;2.64,-8.61,;3.41,-7.25,;2.64,-5.9,;1.07,-5.91,;.3,-7.26,;1.09,-8.61,;2.1,-10.69,;2.06,-12.23,;.74,-12.97,;-.6,-12.19,;-.58,-10.65,;.77,-9.89,;6.81,-15.92,;8.35,-15.99,;10.24,-15.76,;9.85,-17.24,;10.92,-18.3,;12.38,-17.91,;13.45,-19,;12.78,-16.44,;11.71,-15.38,)| Show InChI InChI=1S/C27H30ClNO/c28-25-15-13-24(14-16-25)27(30)17-20-29(21-18-27)19-7-12-26(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-6,8-11,13-16,26,30H,7,12,17-21H2/p+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-MIP-1 alpha binding to recombinant human C-C chemokine receptor type 1 expressed in HEK293 cells				J Med Chem 42: 4680-94 (1999) BindingDB Entry DOI: 10.7270/Q2125TCC
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50082730 (4-(4-Chloro-phenyl)-1-(4,4-diphenyl-butyl)-4-hydro...) Show SMILES OC1(CC[NH+](CCCC(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 |(10.24,-13.6,;9.18,-14.69,;8.45,-13.32,;6.91,-13.28,;5.59,-14.67,;4.76,-13.81,;4.76,-12.27,;3.43,-11.48,;3.43,-9.94,;2.64,-8.61,;3.41,-7.25,;2.64,-5.9,;1.07,-5.91,;.3,-7.26,;1.09,-8.61,;2.1,-10.69,;2.06,-12.23,;.74,-12.97,;-.6,-12.19,;-.58,-10.65,;.77,-9.89,;6.81,-15.92,;8.35,-15.99,;10.24,-15.76,;9.85,-17.24,;10.92,-18.3,;12.38,-17.91,;13.45,-19,;12.78,-16.44,;11.71,-15.38,)| Show InChI InChI=1S/C27H30ClNO/c28-25-15-13-24(14-16-25)27(30)17-20-29(21-18-27)19-7-12-26(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-6,8-11,13-16,26,30H,7,12,17-21H2/p+1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of MIP-1-alpha-induced intracellular calcium mobilization in HEK293 cells expressing human CCR1 receptor				J Med Chem 42: 4680-94 (1999) BindingDB Entry DOI: 10.7270/Q2125TCC
					More data for this Ligand-Target Pair