BDBM50082913 2-[(5-{[(2-Cyclohexyl-ethyl)-methyl-amino]-methyl}-2'-methyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-lithium-butarate::CHEMBL362186

SMILES: CSCC[C@H](NC(=O)c1ccc(CN(C)CCC2CCCCC2)cc1-c1ccccc1C)C([O-])=O

InChI Key: InChIKey=DGZFYSHLPNCUEY-MHZLTWQESA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50082913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT)/farnesyltransferase beta subunit (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50082913 (2-[(5-{[(2-Cyclohexyl-ethyl)-methyl-amino]-methyl}...) Show SMILES CSCC[C@H](NC(=O)c1ccc(CN(C)CCC2CCCCC2)cc1-c1ccccc1C)C([O-])=O Show InChI InChI=1S/C29H40N2O3S/c1-21-9-7-8-12-24(21)26-19-23(20-31(2)17-15-22-10-5-4-6-11-22)13-14-25(26)28(32)30-27(29(33)34)16-18-35-3/h7-9,12-14,19,22,27H,4-6,10-11,15-18,20H2,1-3H3,(H,30,32)(H,33,34)/p-1/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.870	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against Farnesyltransferase (FTase)				J Med Chem 42: 4844-52 (1999) BindingDB Entry DOI: 10.7270/Q2WW7GWR
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