BDBM50083141 CHEMBL356808::Indan-1-yl-{1-[3-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-propyl]-piperidin-4-ylmethyl}-amine

SMILES: C(CN1CCC(CNC2CCc3ccccc23)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1

InChI Key: InChIKey=OPCBJKMFFMUBPI-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50083141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50083141 (CHEMBL356808 | Indan-1-yl-{1-[3-(5-[1,2,4]triazol-...) Show SMILES C(CN1CCC(CNC2CCc3ccccc23)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C28H34N6/c1-2-6-25-22(4-1)7-9-27(25)29-17-21-11-14-33(15-12-21)13-3-5-23-18-30-28-10-8-24(16-26(23)28)34-19-31-32-20-34/h1-2,4,6,8,10,16,18-21,27,29-30H,3,5,7,9,11-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Agonist-induced [35S]- GTPgammaS binding in CHO cells stably transfected with 5-hydroxytryptamine 1D receptor				J Med Chem 42: 4981-5001 (2000) BindingDB Entry DOI: 10.7270/Q20P0Z77
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50083141 (CHEMBL356808 | Indan-1-yl-{1-[3-(5-[1,2,4]triazol-...) Show SMILES C(CN1CCC(CNC2CCc3ccccc23)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C28H34N6/c1-2-6-25-22(4-1)7-9-27(25)29-17-21-11-14-33(15-12-21)13-3-5-23-18-30-28-10-8-24(16-26(23)28)34-19-31-32-20-34/h1-2,4,6,8,10,16,18-21,27,29-30H,3,5,7,9,11-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1D receptor stably expressed in CHO cells				J Med Chem 42: 4981-5001 (2000) BindingDB Entry DOI: 10.7270/Q20P0Z77
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50083141 (CHEMBL356808 | Indan-1-yl-{1-[3-(5-[1,2,4]triazol-...) Show SMILES C(CN1CCC(CNC2CCc3ccccc23)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1 Show InChI InChI=1S/C28H34N6/c1-2-6-25-22(4-1)7-9-27(25)29-17-21-11-14-33(15-12-21)13-3-5-23-18-30-28-10-8-24(16-26(23)28)34-19-31-32-20-34/h1-2,4,6,8,10,16,18-21,27,29-30H,3,5,7,9,11-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cells				J Med Chem 42: 4981-5001 (2000) BindingDB Entry DOI: 10.7270/Q20P0Z77
					More data for this Ligand-Target Pair