BDBM50083232 1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-dihydro-benzoimidazol-2-one::CHEMBL146013

SMILES: CCn1c2ccccc2n(C2CCN(CC3CCCCCCC3)CC2)c1=O

InChI Key: InChIKey=KCQGDRBBVRBNEE-UHFFFAOYSA-N

Data: 5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50083232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50083232 (1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...) Show SMILES CCn1c2ccccc2n(C2CCN(CC3CCCCCCC3)CC2)c1=O Show InChI InChI=1S/C23H35N3O/c1-2-25-21-12-8-9-13-22(21)26(23(25)27)20-14-16-24(17-15-20)18-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-20H,2-7,10-11,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-Tyr14-nociceptin binding to human Opioid receptor like 1 (opioid receptor like 1) in CHO cells				J Med Chem 42: 5061-3 (2000) BindingDB Entry DOI: 10.7270/Q2MC8Z69
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50083232 (1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...) Show SMILES CCn1c2ccccc2n(C2CCN(CC3CCCCCCC3)CC2)c1=O Show InChI InChI=1S/C23H35N3O/c1-2-25-21-12-8-9-13-22(21)26(23(25)27)20-14-16-24(17-15-20)18-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-20H,2-7,10-11,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H][D-Ala2,D-Leu5]enkephalin binding to human Opioid receptor delta 1 in CHO cells				J Med Chem 42: 5061-3 (2000) BindingDB Entry DOI: 10.7270/Q2MC8Z69
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50083232 (1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...) Show SMILES CCn1c2ccccc2n(C2CCN(CC3CCCCCCC3)CC2)c1=O Show InChI InChI=1S/C23H35N3O/c1-2-25-21-12-8-9-13-22(21)26(23(25)27)20-14-16-24(17-15-20)18-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-20H,2-7,10-11,14-18H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-diprenorphine binding to human Opioid receptor mu 1 in CHO cells				J Med Chem 42: 5061-3 (2000) BindingDB Entry DOI: 10.7270/Q2MC8Z69
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50083232 (1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...) Show SMILES CCn1c2ccccc2n(C2CCN(CC3CCCCCCC3)CC2)c1=O Show InChI InChI=1S/C23H35N3O/c1-2-25-21-12-8-9-13-22(21)26(23(25)27)20-14-16-24(17-15-20)18-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-20H,2-7,10-11,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity in CHO cells stably expressing cloned human Opioid receptor kappa 1 by displacing radioligand [3H]U-69593				J Med Chem 42: 5061-3 (2000) BindingDB Entry DOI: 10.7270/Q2MC8Z69
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50083232 (1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...) Show SMILES CCn1c2ccccc2n(C2CCN(CC3CCCCCCC3)CC2)c1=O Show InChI InChI=1S/C23H35N3O/c1-2-25-21-12-8-9-13-22(21)26(23(25)27)20-14-16-24(17-15-20)18-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-20H,2-7,10-11,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cells				J Med Chem 42: 5061-3 (2000) BindingDB Entry DOI: 10.7270/Q2MC8Z69
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50083232 (1-(1-Cyclooctylmethyl-piperidin-4-yl)-3-ethyl-1,3-...) Show SMILES CCn1c2ccccc2n(C2CCN(CC3CCCCCCC3)CC2)c1=O Show InChI InChI=1S/C23H35N3O/c1-2-25-21-12-8-9-13-22(21)26(23(25)27)20-14-16-24(17-15-20)18-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-20H,2-7,10-11,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity of the compound measured by GTPgammaS binding against Opioid receptor like 1 in CHO cells				J Med Chem 42: 5061-3 (2000) BindingDB Entry DOI: 10.7270/Q2MC8Z69
					More data for this Ligand-Target Pair