BDBM50083286 1-Adamantan-1-yl-3-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-urea; Dihydrochloride::CHEMBL538791

SMILES: COc1ccccc1N1CCN(CCCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1

InChI Key: InChIKey=HTZQCKIHMRMSJH-OVZPOALRSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50083286 (1-Adamantan-1-yl-3-{3-[4-(2-methoxy-phenyl)-pipera...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 |TLB:26:25:28:21.20.22,26:21:28:25.27.24,18:19:24:21.26.22,THB:18:19:25.26.24:22,27:19:25.26.24:22,20:19:24:21.26.22| Show InChI InChI=1S/C25H38N4O2/c1-31-23-6-3-2-5-22(23)29-11-9-28(10-12-29)8-4-7-26-24(30)27-25-16-19-13-20(17-25)15-21(14-19)18-25/h2-3,5-6,19-21H,4,7-18H2,1H3,(H2,26,27,30)/t19-,20+,21-,25?	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50083286 (1-Adamantan-1-yl-3-{3-[4-(2-methoxy-phenyl)-pipera...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 |TLB:26:25:28:21.20.22,26:21:28:25.27.24,18:19:24:21.26.22,THB:18:19:25.26.24:22,27:19:25.26.24:22,20:19:24:21.26.22| Show InChI InChI=1S/C25H38N4O2/c1-31-23-6-3-2-5-22(23)29-11-9-28(10-12-29)8-4-7-26-24(30)27-25-16-19-13-20(17-25)15-21(14-19)18-25/h2-3,5-6,19-21H,4,7-18H2,1H3,(H2,26,27,30)/t19-,20+,21-,25?	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against rat limbic tissue Dopamine receptor D2				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
					More data for this Ligand-Target Pair