BDBM50083296 CHEMBL554204::N-Adamantan-1-yl-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propionamide; Dihydrochloride

SMILES: COc1ccccc1N1CCN(CCC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1

InChI Key: InChIKey=BUNRSIAHLPGQRT-GUHGBLDKSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50083296 (CHEMBL554204 | N-Adamantan-1-yl-3-[4-(2-methoxy-ph...) Show SMILES COc1ccccc1N1CCN(CCC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 |TLB:16:17:23.24.22:20,THB:16:17:22:19.24.20,25:17:23.24.22:20,18:17:22:19.24.20,18:19:17.26.25:22| Show InChI InChI=1S/C24H35N3O2/c1-29-22-5-3-2-4-21(22)27-10-8-26(9-11-27)7-6-23(28)25-24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3,(H,25,28)/t18-,19+,20-,24?	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptor				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50083296 (CHEMBL554204 | N-Adamantan-1-yl-3-[4-(2-methoxy-ph...) Show SMILES COc1ccccc1N1CCN(CCC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 |TLB:16:17:23.24.22:20,THB:16:17:22:19.24.20,25:17:23.24.22:20,18:17:22:19.24.20,18:19:17.26.25:22| Show InChI InChI=1S/C24H35N3O2/c1-29-22-5-3-2-4-21(22)27-10-8-26(9-11-27)7-6-23(28)25-24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3,(H,25,28)/t18-,19+,20-,24?	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against rat limbic tissue Dopamine receptor D2				J Med Chem 42: 5077-94 (2000) BindingDB Entry DOI: 10.7270/Q2C82B0P
					More data for this Ligand-Target Pair