BDBM50083563 1-{4-[5-amino(imino)methylaminobenzo[b]furan-2-ylcarbonyl]hexahydro-1-pyrazinyl}-2-[4-(2-{4-[5-amino(imino)methylaminobenzo[b]furan-2-ylcarbonyl]hexahydro-1-pyrazinyl}-2-oxoethoxy)phenoxy]-1-ethanone::CHEMBL111400

SMILES: [#7]\[#6](-[#7])=[#7]/c1ccc2oc(cc2c1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6]-[#8]-c1ccc(-[#8]-[#6]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-c2cc3cc(ccc3o2)\[#7]=[#6](/[#7])-[#7])cc1

InChI Key: InChIKey=RNOSLBKUOATLNM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50083563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50083563 (1-{4-[5-amino(imino)methylaminobenzo[b]furan-2-ylc...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1ccc2oc(cc2c1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6]-[#8]-c1ccc(-[#8]-[#6]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-c2cc3cc(ccc3o2)\[#7]=[#6](/[#7])-[#7])cc1 Show InChI InChI=1S/C38H40N10O8/c39-37(40)43-25-1-7-29-23(17-25)19-31(55-29)35(51)47-13-9-45(10-14-47)33(49)21-53-27-3-5-28(6-4-27)54-22-34(50)46-11-15-48(16-12-46)36(52)32-20-24-18-26(44-38(41)42)2-8-30(24)56-32/h1-8,17-20H,9-16,21-22H2,(H4,39,40,43)(H4,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL					Assay Description Inhibition of tryptase activity				Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50083563 (1-{4-[5-amino(imino)methylaminobenzo[b]furan-2-ylc...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1ccc2oc(cc2c1)-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6]-[#8]-c1ccc(-[#8]-[#6]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-c2cc3cc(ccc3o2)\[#7]=[#6](/[#7])-[#7])cc1 Show InChI InChI=1S/C38H40N10O8/c39-37(40)43-25-1-7-29-23(17-25)19-31(55-29)35(51)47-13-9-45(10-14-47)33(49)21-53-27-3-5-28(6-4-27)54-22-34(50)46-11-15-48(16-12-46)36(52)32-20-24-18-26(44-38(41)42)2-8-30(24)56-32/h1-8,17-20H,9-16,21-22H2,(H4,39,40,43)(H4,41,42,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3
					More data for this Ligand-Target Pair