BDBM50083591 4-{5-[(4-Benzenesulfonyl-3-methyl-phenylamino)-methyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL109303

SMILES: Cc1cc(NCc2cncn2Cc2ccc(cc2)C#N)ccc1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=QTPUIMUFPJCBFZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Bos taurus (bovine))	BDBM50083591 (4-{5-[(4-Benzenesulfonyl-3-methyl-phenylamino)-met...) Show SMILES Cc1cc(NCc2cncn2Cc2ccc(cc2)C#N)ccc1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C25H22N4O2S/c1-19-13-22(11-12-25(19)32(30,31)24-5-3-2-4-6-24)28-16-23-15-27-18-29(23)17-21-9-7-20(14-26)8-10-21/h2-13,15,18,28H,16-17H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of bovine Farnesyltransferase in vitro.				Bioorg Med Chem Lett 9: 3301-6 (2000) BindingDB Entry DOI: 10.7270/Q2Q52NT7
					More data for this Ligand-Target Pair