BDBM50083625 CHEMBL320553::{3-[2-(4-Methoxy-phenyl)-ethyl]-2-phenyl-1H-indol-5-yl}-acetic acid::{3-[2-(4-Methoxy-phenyl)-ethyl]-2-phenyl-1H-indol-5-yl}-acetic acid(GW 0207)
SMILES: COc1ccc(CCc2c([nH]c3ccc(CC(O)=O)cc23)-c2ccccc2)cc1
InChI Key: InChIKey=YZLHLVJLTOPOHC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50083625 (CHEMBL320553 | {3-[2-(4-Methoxy-phenyl)-ethyl]-2-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Binding affinity against Peroxisome proliferator activated receptor gamma (PPAR gamma) | Bioorg Med Chem Lett 9: 3329-34 (2000) BindingDB Entry DOI: 10.7270/Q2FN15FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50083625 (CHEMBL320553 | {3-[2-(4-Methoxy-phenyl)-ethyl]-2-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Binding affinity against human Peroxisome proliferator activated receptor gamma (PPAR gamma) | Bioorg Med Chem Lett 9: 3329-34 (2000) BindingDB Entry DOI: 10.7270/Q2FN15FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50083625 (CHEMBL320553 | {3-[2-(4-Methoxy-phenyl)-ethyl]-2-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Transcriptional activation of peroxisome proliferator activated receptor gamma | Bioorg Med Chem Lett 9: 3329-34 (2000) BindingDB Entry DOI: 10.7270/Q2FN15FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50083625 (CHEMBL320553 | {3-[2-(4-Methoxy-phenyl)-ethyl]-2-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description Inhibitory concentration of the PPAR gamma) | Bioorg Med Chem Lett 9: 3329-34 (2000) BindingDB Entry DOI: 10.7270/Q2FN15FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Mus musculus) | BDBM50083625 (CHEMBL320553 | {3-[2-(4-Methoxy-phenyl)-ethyl]-2-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Agonist activity for murine PPAR gamma receptor in transcriptional activation assay | J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50083625 (CHEMBL320553 | {3-[2-(4-Methoxy-phenyl)-ethyl]-2-p...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research & Development Curated by ChEMBL | Assay Description Agonist activity for Human PPAR gamma receptor in transcriptional activation assay | J Med Chem 43: 527-50 (2000) BindingDB Entry DOI: 10.7270/Q2H994DT | |||||||||||
More data for this Ligand-Target Pair |