BDBM50083678 1-(5-Bromo-pyridin-2-yl)-3-(2-furan-2-yl-ethyl)-thiourea::CHEMBL114598

SMILES: Brc1ccc(NC(=S)NCCc2ccco2)nc1

InChI Key: InChIKey=YMRKJDSMUKZTBB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50083678 (1-(5-Bromo-pyridin-2-yl)-3-(2-furan-2-yl-ethyl)-th...) Show SMILES Brc1ccc(NC(=S)NCCc2ccco2)nc1 Show InChI InChI=1S/C12H12BrN3OS/c13-9-3-4-11(15-8-9)16-12(18)14-6-5-10-2-1-7-17-10/h1-4,7-8H,5-6H2,(H2,14,15,16,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay system				Bioorg Med Chem Lett 9: 3411-6 (2000) BindingDB Entry DOI: 10.7270/Q2SX6CD8
					More data for this Ligand-Target Pair