BDBM50083951 4-(3-Bromo-phenyl)-2-hydroxy-4-oxo-but-2-enoic acid methyl ester::CHEMBL283135

SMILES: COC(=O)C(=O)CC(=O)c1cccc(Br)c1

InChI Key: InChIKey=JEJFZQTXCRUDGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kynurenine 3-monooxygenase (Rattus norvegicus)	BDBM50083951 (4-(3-Bromo-phenyl)-2-hydroxy-4-oxo-but-2-enoic aci...) Show SMILES COC(=O)C(=O)CC(=O)c1cccc(Br)c1 Show InChI InChI=1S/C11H9BrO4/c1-16-11(15)10(14)6-9(13)7-3-2-4-8(12)5-7/h2-5H,6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description Inhibition of Kynurenine-3-hydroxylase enzyme isolated from the rat liver				J Med Chem 43: 123-7 (2000) BindingDB Entry DOI: 10.7270/Q2RX9B9B
					More data for this Ligand-Target Pair