BDBM50083975 CHEMBL536706::N-(5-Amino-pentyl)-2-(4-oxo-2-phenethyl-6-phenyl-4H-quinazolin-3-yl)-acetamide; hydrochloride

SMILES: NCCCCCNC(=O)Cn1c(CCc2ccccc2)nc2ccc(cc2c1=O)-c1ccccc1

InChI Key: InChIKey=DKSCZFUABBXMJO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50083975 (CHEMBL536706 | N-(5-Amino-pentyl)-2-(4-oxo-2-phene...) Show SMILES NCCCCCNC(=O)Cn1c(CCc2ccccc2)nc2ccc(cc2c1=O)-c1ccccc1 Show InChI InChI=1S/C29H32N4O2/c30-18-8-3-9-19-31-28(34)21-33-27(17-14-22-10-4-1-5-11-22)32-26-16-15-24(20-25(26)29(33)35)23-12-6-2-7-13-23/h1-2,4-7,10-13,15-16,20H,3,8-9,14,17-19,21,30H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor				Bioorg Med Chem Lett 10: 5-8 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KDR
					More data for this Ligand-Target Pair