BDBM50083977 6-Amino-2-[2-(6-chloro-2-naphthalen-2-yl-4-oxo-4H-quinazolin-3-yl)-acetylamino]-hexanoic acid methyl ester; hydrochloride::CHEMBL540093

SMILES: COC(=O)C(CCCCN)NC(=O)Cn1c(nc2ccc(Cl)cc2c1=O)-c1ccc2ccccc2c1

InChI Key: InChIKey=KHYJHICNVDZIRN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50083977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ghrelin receptor (Homo sapiens (Human))	BDBM50083977 (6-Amino-2-[2-(6-chloro-2-naphthalen-2-yl-4-oxo-4H-...) Show SMILES COC(=O)C(CCCCN)NC(=O)Cn1c(nc2ccc(Cl)cc2c1=O)-c1ccc2ccccc2c1 Show InChI InChI=1S/C27H27ClN4O4/c1-36-27(35)23(8-4-5-13-29)30-24(33)16-32-25(19-10-9-17-6-2-3-7-18(17)14-19)31-22-12-11-20(28)15-21(22)26(32)34/h2-3,6-7,9-12,14-15,23H,4-5,8,13,16,29H2,1H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor				Bioorg Med Chem Lett 10: 5-8 (2000) BindingDB Entry DOI: 10.7270/Q2DV1KDR
					More data for this Ligand-Target Pair