BDBM50084106 CHEMBL77513::Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-hydroxy-7-phenyl-hept-1-enyl)-cyclohexyl]-acetate

SMILES: OC(CCCCc1ccccc1)\C=C\[C@H]1CCC[C@@](O)(CC([O-])=O)C1

InChI Key: InChIKey=HGDRLKMEWSBKRS-MHUYJMBKSA-M

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50084106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50084106 (CHEMBL77513 | Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-...) Show SMILES OC(CCCCc1ccccc1)\C=C\[C@H]1CCC[C@@](O)(CC([O-])=O)C1 Show InChI InChI=1S/C21H30O4/c22-19(11-5-4-9-17-7-2-1-3-8-17)13-12-18-10-6-14-21(25,15-18)16-20(23)24/h1-3,7-8,12-13,18-19,22,25H,4-6,9-11,14-16H2,(H,23,24)/p-1/b13-12+/t18-,19?,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand				Bioorg Med Chem Lett 6: 2349-2354 (1996) Article DOI: 10.1016/0960-894X(96)00424-6 BindingDB Entry DOI: 10.7270/Q23T9H7K
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50084106 (CHEMBL77513 | Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-...) Show SMILES OC(CCCCc1ccccc1)\C=C\[C@H]1CCC[C@@](O)(CC([O-])=O)C1 Show InChI InChI=1S/C21H30O4/c22-19(11-5-4-9-17-7-2-1-3-8-17)13-12-18-10-6-14-21(25,15-18)16-20(23)24/h1-3,7-8,12-13,18-19,22,25H,4-6,9-11,14-16H2,(H,23,24)/p-1/b13-12+/t18-,19?,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand				Bioorg Med Chem Lett 6: 2349-2354 (1996) Article DOI: 10.1016/0960-894X(96)00424-6 BindingDB Entry DOI: 10.7270/Q23T9H7K
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 2 (Homo sapiens)	BDBM50084106 (CHEMBL77513 | Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-...) Show SMILES OC(CCCCc1ccccc1)\C=C\[C@H]1CCC[C@@](O)(CC([O-])=O)C1 Show InChI InChI=1S/C21H30O4/c22-19(11-5-4-9-17-7-2-1-3-8-17)13-12-18-10-6-14-21(25,15-18)16-20(23)24/h1-3,7-8,12-13,18-19,22,25H,4-6,9-11,14-16H2,(H,23,24)/p-1/b13-12+/t18-,19?,21+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
CNRS 5074 Curated by ChEMBL					Assay Description Inhibition of binding of [3H]LTB4 (1 nM) to intact human polymorphonuclear leukocytes (PMNs)				J Med Chem 42: 5289-310 (1999) Article DOI: 10.1021/jm9910573 BindingDB Entry DOI: 10.7270/Q25Q4ZT8
					More data for this Ligand-Target Pair
Leukotriene B4 receptor 2 (Homo sapiens)	BDBM50084106 (CHEMBL77513 | Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-...) Show SMILES OC(CCCCc1ccccc1)\C=C\[C@H]1CCC[C@@](O)(CC([O-])=O)C1 Show InChI InChI=1S/C21H30O4/c22-19(11-5-4-9-17-7-2-1-3-8-17)13-12-18-10-6-14-21(25,15-18)16-20(23)24/h1-3,7-8,12-13,18-19,22,25H,4-6,9-11,14-16H2,(H,23,24)/p-1/b13-12+/t18-,19?,21+/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CNRS 5074 Curated by ChEMBL					Assay Description Inhibition of binding of [3H]LTB4 (1 nM) to intact human polymorphonuclear leukocytes (PMNs)				J Med Chem 42: 5289-310 (1999) Article DOI: 10.1021/jm9910573 BindingDB Entry DOI: 10.7270/Q25Q4ZT8
					More data for this Ligand-Target Pair
Leukotriene B4 receptor (Homo sapiens (Human))	BDBM50084106 (CHEMBL77513 | Sodium; [(1S,3S)-1-hydroxy-3-((E)-3-...) Show SMILES OC(CCCCc1ccccc1)\C=C\[C@H]1CCC[C@@](O)(CC([O-])=O)C1 Show InChI InChI=1S/C21H30O4/c22-19(11-5-4-9-17-7-2-1-3-8-17)13-12-18-10-6-14-21(25,15-18)16-20(23)24/h1-3,7-8,12-13,18-19,22,25H,4-6,9-11,14-16H2,(H,23,24)/p-1/b13-12+/t18-,19?,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibitory activity against LTB4 receptor in human neutrophil membranes using [3H]- LTB4 as radioligand				Bioorg Med Chem Lett 6: 2349-2354 (1996) Article DOI: 10.1016/0960-894X(96)00424-6 BindingDB Entry DOI: 10.7270/Q23T9H7K
					More data for this Ligand-Target Pair