BDBM50084494 CHEMBL315879::N-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-butyl}-3-methoxy-benzamide::N-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-butyl}-3-methoxy-benzamide (HCL .5/4H2O)
SMILES: COc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1ccc(Cl)cc1
InChI Key: InChIKey=AUKXTTDRFKLJIH-UHFFFAOYSA-N
Data: 7 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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D(3) dopamine receptor (Rattus norvegicus (Rat)) | BDBM50084494 (CHEMBL315879 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Binding affinity towards Dopamine receptor D3 of rat using [3H]spiroperidol as radioligand | J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50084494 (CHEMBL315879 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligand | J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50084494 (CHEMBL315879 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitá di Bari Curated by ChEMBL | Assay Description In vitro binding affinity at human Dopamine receptor D4.4 by [3H]-YM-09151-2 displacement. | J Med Chem 43: 270-7 (2000) BindingDB Entry DOI: 10.7270/Q2610ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50084494 (CHEMBL315879 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 397 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitá di Bari Curated by ChEMBL | Assay Description In vitro binding affinity at 5-hydroxytryptamine receptor 1A receptor in rat hippocampal membranes by [3H]-8-OH-DPAT displacement. | J Med Chem 43: 270-7 (2000) BindingDB Entry DOI: 10.7270/Q2610ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50084494 (CHEMBL315879 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 397 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat hippocampal membranes | J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50084494 (CHEMBL315879 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitá di Bari Curated by ChEMBL | Assay Description In vitro binding affinity at human Dopamine receptor D2 (long) by [3H]-spiroperidol displacement. | J Med Chem 43: 270-7 (2000) BindingDB Entry DOI: 10.7270/Q2610ZH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50084494 (CHEMBL315879 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari Curated by ChEMBL | Assay Description Binding affinity towards human Dopamine receptor D2 using [3H]spiroperidol as radioligand | J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC | |||||||||||
More data for this Ligand-Target Pair |