BDBM50084659 3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthalen-2-yloxy)-phenyl]-2-hydroxy-benzamide::CHEMBL115114

SMILES: Oc1c(Br)cc(Cl)cc1C(=O)Nc1cc(Cl)ccc1Oc1ccc2ccccc2c1Cl

InChI Key: InChIKey=UICKPIYIRFGAGL-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50084659   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
poly(ADP-ribose) glycohydrolase (PARG) (Homo sapiens (Human))	BDBM50084659 (3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...) Show SMILES Oc1c(Br)cc(Cl)cc1C(=O)Nc1cc(Cl)ccc1Oc1ccc2ccccc2c1Cl Show InChI InChI=1S/C23H13BrCl3NO3/c24-17-10-14(26)9-16(22(17)29)23(30)28-18-11-13(25)6-8-19(18)31-20-7-5-12-3-1-2-4-15(12)21(20)27/h1-11,29H,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of PARG using [alpha-32P]ADP-ribose polymers after 5 mins by TRAP assay				J Med Chem 54: 5403-13 (2011) Article DOI: 10.1021/jm200325s BindingDB Entry DOI: 10.7270/Q2416XFG
					More data for this Ligand-Target Pair
Hepatitis C virus serine protease, NS3/NS4A (Hepatitis C virus)	BDBM50084659 (3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...) Show SMILES Oc1c(Br)cc(Cl)cc1C(=O)Nc1cc(Cl)ccc1Oc1ccc2ccccc2c1Cl Show InChI InChI=1S/C23H13BrCl3NO3/c24-17-10-14(26)9-16(22(17)29)23(30)28-18-11-13(25)6-8-19(18)31-20-7-5-12-3-1-2-4-15(12)21(20)27/h1-11,29H,(H,28,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibitory concentration against hepatitis C virus NS3 protease				J Med Chem 48: 1-20 (2005) Article DOI: 10.1021/jm0400101 BindingDB Entry DOI: 10.7270/Q2XP75Q1
					More data for this Ligand-Target Pair
Human rhinovirus A protease (Human rhinovirus B)	BDBM50084659 (3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...) Show SMILES Oc1c(Br)cc(Cl)cc1C(=O)Nc1cc(Cl)ccc1Oc1ccc2ccccc2c1Cl Show InChI InChI=1S/C23H13BrCl3NO3/c24-17-10-14(26)9-16(22(17)29)23(30)28-18-11-13(25)6-8-19(18)31-20-7-5-12-3-1-2-4-15(12)21(20)27/h1-11,29H,(H,28,30)	MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Queensland Curated by ChEMBL					Assay Description Inhibitory concentration against Protease				J Med Chem 43: 305-41 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2JD4XH4
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50084659 (3-Bromo-5-chloro-N-[5-chloro-2-(1-chloro-naphthale...) Show SMILES Oc1c(Br)cc(Cl)cc1C(=O)Nc1cc(Cl)ccc1Oc1ccc2ccccc2c1Cl Show InChI InChI=1S/C23H13BrCl3NO3/c24-17-10-14(26)9-16(22(17)29)23(30)28-18-11-13(25)6-8-19(18)31-20-7-5-12-3-1-2-4-15(12)21(20)27/h1-11,29H,(H,28,30)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of PARP-1 using [32P]-NAD+ after 15 mins				J Med Chem 54: 5403-13 (2011) Article DOI: 10.1021/jm200325s BindingDB Entry DOI: 10.7270/Q2416XFG
					More data for this Ligand-Target Pair