BDBM50085037 6-Chloro-4-cyclopropyl-4-cyclopropylethynyl-3,4-dihydro-1H-benzo[1,2,6]thiadiazine 2,2-dioxide::CHEMBL58552

SMILES: Clc1ccc2NS(=O)(=O)NC(C#CC3CC3)(C3CC3)c2c1

InChI Key: InChIKey=HPHZZAFKMHGJKQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50085037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50085037 (6-Chloro-4-cyclopropyl-4-cyclopropylethynyl-3,4-di...) Show SMILES Clc1ccc2NS(=O)(=O)NC(C#CC3CC3)(C3CC3)c2c1 Show InChI InChI=1S/C15H15ClN2O2S/c16-12-5-6-14-13(9-12)15(11-3-4-11,8-7-10-1-2-10)18-21(19,20)17-14/h5-6,9-11,17-18H,1-4H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH
					More data for this Ligand-Target Pair