BDBM50085141 CHEMBL351900::Trifluoro-methanesulfonic acid 8-(3-nitro-phenyl)-[1,7]naphthyridin-6-yl ester

SMILES: [O-][N+](=O)c1cccc(c1)-c1nc(OS(=O)(=O)C(F)(F)F)cc2cccnc12

InChI Key: InChIKey=ZHSRABCDAAITJX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50085141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Homo sapiens (Human))	BDBM50085141 (CHEMBL351900 | Trifluoro-methanesulfonic acid 8-(3...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc(OS(=O)(=O)C(F)(F)F)cc2cccnc12 Show InChI InChI=1S/C15H8F3N3O5S/c16-15(17,18)27(24,25)26-12-8-10-4-2-6-19-13(10)14(20-12)9-3-1-5-11(7-9)21(22)23/h1-8H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiae				J Med Chem 43: 675-82 (2000) BindingDB Entry DOI: 10.7270/Q2N58N3G
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (RAT)	BDBM50085141 (CHEMBL351900 | Trifluoro-methanesulfonic acid 8-(3...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc(OS(=O)(=O)C(F)(F)F)cc2cccnc12 Show InChI InChI=1S/C15H8F3N3O5S/c16-15(17,18)27(24,25)26-12-8-10-4-2-6-19-13(10)14(20-12)9-3-1-5-11(7-9)21(22)23/h1-8H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiae				J Med Chem 43: 675-82 (2000) BindingDB Entry DOI: 10.7270/Q2N58N3G
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 1 (Homo sapiens (Human))	BDBM50085141 (CHEMBL351900 | Trifluoro-methanesulfonic acid 8-(3...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc(OS(=O)(=O)C(F)(F)F)cc2cccnc12 Show InChI InChI=1S/C15H8F3N3O5S/c16-15(17,18)27(24,25)26-12-8-10-4-2-6-19-13(10)14(20-12)9-3-1-5-11(7-9)21(22)23/h1-8H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiae				J Med Chem 43: 675-82 (2000) BindingDB Entry DOI: 10.7270/Q2N58N3G
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50085141 (CHEMBL351900 | Trifluoro-methanesulfonic acid 8-(3...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc(OS(=O)(=O)C(F)(F)F)cc2cccnc12 Show InChI InChI=1S/C15H8F3N3O5S/c16-15(17,18)27(24,25)26-12-8-10-4-2-6-19-13(10)14(20-12)9-3-1-5-11(7-9)21(22)23/h1-8H	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiae				J Med Chem 43: 675-82 (2000) BindingDB Entry DOI: 10.7270/Q2N58N3G
					More data for this Ligand-Target Pair